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A tiny dose of a diabetes drug helped sick rat hearts beat better—even without losing weight
Original Title
Low Dose GLP-1 Therapy Attenuates Pathological Cardiac and Hepatic Remodelling in HFpEF Independent of Weight Loss
doi:10.1101/2025.09.26.67882916%
Lower Quality
Methodology score · 16/100
Cohort Animal
Fit Body Science breakdown
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What’s the bottom line?
Scientists gave sick, overweight rats a very small amount of a drug called semaglutide—so small it didn’t make them lose weight—but their hearts got stronger, their livers got cleaner, and their bodies became less inflamed.
Score breakdown, methodology, COI, evidence analysis & raw study data