The Study
Cardiovascular safety of testosterone therapy—Insights from the TRAVERSE trial and beyond: A position statement of the European Expert Panel for Testosterone Research
This paper is like a teacher summarizing what other scientists found in their experiments. It doesn’t do any experiments itself, so it can’t say for sure that testosterone is safe—it can only say what other studies and experts think.
Analysis score
Maximum 5 for a narrative review.
Where the score came from
Giving low-testosterone men the right amount of testosterone doesn't make their hearts have more heart attacks or strokes, helps fix low blood count, and slightly improves good cholesterol — but might cause a tiny uptick in irregular heartbeat.
Where does this study sit?
Systematic Reviews & Meta-analyses
Max 100Randomized Trials
Max 90Cohort Studies
Max 72Case-Control
Max 58Cross-Sectional
Max 44Case Reports & Series
Max 30Expert Opinion
Max 51 / 100
Quality score
Based on clinical experience or non-systematic literature reviews. The lowest level of evidence as they are most susceptible to bias and personal perspective.
Key takeaways
Summary
Based on the study abstract and findings.
- 1The heart risks didn't go up — that's reassuring.
- 2The anemia fix is a real bonus.
- 3The slight rise in irregular heartbeat is small and not clearly dangerous yet.
- 4In 5,246 men: no increase in heart attacks, strokes, or heart-related deaths; anemia improved; HDL cholesterol went up a little; atrial fibrillation risk went up slightly.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Andrology
Year
2025
Authors
Michael Zitzmann, G. Rastrelli, R. D. Murray, D. Edwards, Yacov Reisman, P. Rao, Alexander Sahi, T. H. Jones, A. Ferlin, E. Armeni, Emiliano Corpas, J. Cremers, J. David, S. Arver, Leen Antonio, G. Corona
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.