The Study
Microbicidal Activity of Vascular Peroxidase 1 in Human Plasma via Generation of Hypochlorous Acid
This is like a science experiment in a test tube showing that a certain chemical can kill bacteria when mixed with other chemicals. It tells us what can happen in a lab, but not if it works the same way inside our bodies or helps fight infections in real life.
Analysis score
Maximum 44 for a cross-sectional study.
Where the score came from
Scientists found an enzyme in blood that makes a germ-killing chemical like bleach.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 53 / 100
Quality score
Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1This might help our bodies fight infections better.
- 2Enzyme made germ-killing chemical and killed bacteria in tests.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Infection and Immunity
Year
2012
Authors
Hong Li, Zehong Cao, D. Moore, P. Jackson, Stephen Barnes, Stephen Barnes, J. Lambeth, V. Thannickal, G. Cheng
Related Content
Claims (3)
There's a special protein in our blood vessels that can make a chemical called hypochlorous acid when it mixes with hydrogen peroxide and salt, and scientists showed this by testing it on other chemicals.
Certain proteins in blood called VPO1 can kill bacteria using chemicals like chloride and hydrogen peroxide, but this process gets blocked by other substances that stop these proteins from working.
Scientists say there's a special protein called VPO1 that, like another protein MPO, can make a powerful cleaning chemical called hypochlorous acid inside our bodies.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.