How muscles grow and stay strong

Original Title

Physiologic and molecular bases of muscle hypertrophy and atrophy: impact of resistance exercise on human skeletal muscle (protein and exercise dose effects).

Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms

Summary

Muscles stay the same size when the body makes and breaks down muscle at the same rate. Eating protein helps build muscle, and exercise boosts this effect. As people age or don’t move much, their muscles don’t respond as well to food, which can cause muscle loss.

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Surprising Findings

Muscle loss in aging is not due to chronic changes in basal MPS or MPB, but to a blunted response to feeding.

This contradicts the intuitive belief that older muscles waste away because they’re breaking down faster all the time. Instead, the problem is a failure to build after meals.

Practical Takeaways

Combine resistance exercise with protein intake to maximize muscle maintenance, especially if you're aging or inactive.

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