Can watermelon amino acid lower blood pressure?
l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
L-citrulline lowered blood pressure more consistently than L-arginine—even though both boost nitric oxide.
L-arginine has been the go-to NO booster for years. But this meta-analysis, backed by a 2017 crossover trial cited in the full text, shows L-citrulline is better absorbed and more effective at lowering BP despite similar NO increases.
Practical Takeaways
If you want to try L-citrulline for blood pressure, take 6–9g per day for at least 4 weeks and monitor your BP with a home monitor.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
L-citrulline lowered blood pressure more consistently than L-arginine—even though both boost nitric oxide.
L-arginine has been the go-to NO booster for years. But this meta-analysis, backed by a 2017 crossover trial cited in the full text, shows L-citrulline is better absorbed and more effective at lowering BP despite similar NO increases.
Practical Takeaways
If you want to try L-citrulline for blood pressure, take 6–9g per day for at least 4 weeks and monitor your BP with a home monitor.
Publication
Journal
Journal of applied physiology
Year
2015
Authors
S. Bailey, Jamie R. Blackwell, T. Lord, A. Vanhatalo, P. Winyard, A. Jones
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Claims (2)
Taking L-citrulline supplements every day for a few weeks might slightly lower your blood pressure—like a small drop that could help keep your heart healthier.
Taking at least 6 grams of L-citrulline every day might lower your bottom blood pressure number by about 3 points, but taking less than that doesn’t seem to do anything noticeable.