Taking at least 6 grams of L-citrulline every day might lower your bottom blood pressure number by about 3 points, but taking less than that doesn’t seem to do anything noticeable.

59

Pro

0

Against

Evidence from Studies

Supporting (1)

59

Community contributions welcome

59

l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.

Systematic Review With Meta-Analysis

Human

2019 Jan-Feb

This study gave healthy men 6 grams of L-citrulline daily and found their blood pressure went down, which matches the claim that this dose helps lower blood pressure — but it didn’t test smaller doses, so it supports the idea that only higher doses work.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.

Score: 59

DOI: 10.1152/japplphysiol.00192.2014

Similar Assertions

Taking L-citrulline supplements every day for a few weeks might slightly lower your blood pressure—like a small drop that could help keep your heart healthier.

59

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92%

Taking L-citrulline pills or getting it from watermelon might help lower your blood pressure a little—especially if you already have high blood pressure and take it for at least six weeks.

2

0

86%

Taking a specific dose of L-citrulline for 10 days doesn’t make you bike harder, faster, or feel less tired—even though some people think it might help. Your heart, lungs, and muscles act the same as if you didn’t take it.

53

0

76%

Taking L-citrulline pills for 10 days at a specific dose doesn’t seem to make healthy young adults feel sick—only a few people might get a little stomach upset.

53

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75%