Cancer study pulled for problems
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Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The study was cited 7 times before being retracted
Most retracted studies get few citations, but this one had enough traction to be cited before being pulled
Practical Takeaways
Always check if a study is retracted before citing it in your work
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The study was cited 7 times before being retracted
Most retracted studies get few citations, but this one had enough traction to be cited before being pulled
Practical Takeaways
Always check if a study is retracted before citing it in your work
Publication
Related Content
Claims (10)
Using a special virus to deliver a genetic tool that blocks ER-α gene activity successfully lowered ER-α levels in liver cancer cells within a day or two.
Blocking ER-α in liver cancer cells made them grow much slower in lab tests, with about a third less growth in some tests and half fewer colonies forming in soft agar.
When ER-α was blocked in liver cancer cells, fewer cells were in the DNA-copying phase of the cell cycle and more cells died through programmed cell death.
Using a virus to deliver the genetic tool worked better than other methods, with about 80% of liver cancer cells taking up the treatment successfully.
When ER-α was blocked in liver cancer cells, fewer cells were in the DNA-copying phase and more cells died, which explains why the cells grew slower.