The Study
Dermatophagoides farinae-1-derived peptides and HLA molecules recognized by T cells from atopic individuals.
This study gave 14 strong guys two different diets and saw what happened — but it only tested them, not everyone. So we can say this diet probably didn’t hurt them, but we can’t say it won’t hurt anyone else.
Analysis score
Maximum 90 for a randomized controlled trial.
Where the score came from
Scientists gave 14 strong men a lot more protein than usual for a year to see if it hurt their kidneys, liver, or made them gain fat.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 554 / 100
Quality score
Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Even though they ate more calories and protein, they didn’t gain fat or get sick — suggesting high protein is safe for trained athletes.
- 2They ate 3.32 grams of protein per kg of body weight daily — over 3 times the daily recommendation — and saw no increase in fat, no harm to kidneys or liver, and no bad changes in cholesterol.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
International archives of allergy and immunology
Year
1997
Authors
T. Matsuoka, H. Kohrogi, M. Ando, Y. Nishimura, S. Matsushita
Related Content
Claims (4)
In healthy men who lift weights, eating a high-protein diet for a year does not damage the kidneys, liver, or blood fats, and does not change body composition, even though they eat more protein and more total calories than usual.
In men who regularly lift weights, consuming up to 3.32 grams of protein per kilogram of body weight daily for one year does not change blood markers of kidney function, including urea nitrogen, creatinine, and estimated glomerular filtration rate.
In men who regularly lift weights, consuming up to 3.32 grams of protein per kilogram of body weight daily for one year does not change liver function blood markers such as alanine transaminase, aspartate transaminase, or total bilirubin.
In men who regularly lift weights, eating a high-protein diet of 3.32 grams per kilogram of body weight per day for one year does not change levels of total cholesterol, LDL cholesterol, HDL cholesterol, or triglycerides, even when they consume more than 600 mg of cholesterol per day.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.