Why high bone hormone might mean weak hands in older diabetics
Sex Differences and Positive Dose-Response Relationships between Serum Osteocalcin Levels and Low Muscle Strength
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
In older people with diabetes, higher levels of a bone hormone called osteocalcin were linked to weaker hand grip, especially in women.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
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Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
In older people with diabetes, higher levels of a bone hormone called osteocalcin were linked to weaker hand grip, especially in women.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 540 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Chen PY, Lee YH, Chiang CH, Chang HH, Lu CW, Huang KC
Related Content
Claims (4)
Low grip strength is strongly correlated with increased risk of premature mortality.
People with diabetes who have more osteocalcin in their blood tend to have weaker hand grip, especially women, but we don’t know if the hormone causes weakness or if weakness changes the hormone.
In older women with diabetes, higher levels of a bone protein called osteocalcin are more strongly linked to weak hand grip than in men — especially when levels are above 15 ng/mL.
The more osteocalcin in the blood of older adults with diabetes, the weaker their hand grip tends to be — and this pattern gets stronger as levels go up.