Why eating more salt might lower your blood pressure
Dietary Sodium-Regulated Plasma SVEP1 and Inverse Salt Sensitivity
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Publication
Journal
Hypertension
Year
2026
Authors
S. Ramachandrarao, Christiana Hench, Andrea M. Berrido, R. Auchus, Jonathan Troost, John Darcy, J. B. Byrd
Related Content
Claims (6)
Eating more salt won't keep your blood pressure high over time because your body naturally adjusts to keep things balanced.
When you eat a lot of salt, two proteins in your body—SVEP1 and NT-proBNP—go up together, and it looks like this is because your blood volume increases, not because of the salt directly.
Eating a lot of salt for a week can raise a specific protein in your blood called SVEP1 and lower your blood pressure a little bit — scientists think this protein might help your blood vessels relax and get rid of extra fluid.
When people eat a lot of salt, a specific protein in their blood called SVEP1 goes up, and this increase is linked to a drop in blood pressure — more than other known markers like renin or NT-proBNP.
Eating a lot of salt causes your body to rearrange the structural support network around your cells, especially activating processes related to collagen and cell adhesion molecules.