Too much salt makes your gut bugs angry and your blood pressure go up
High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Eating too much salt changes the good bugs in your gut. These angry bugs can make your body inflamed and your blood pressure rise. In mice, giving poop from salty-eaters to clean mice made the clean mice get high blood pressure too.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
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Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Eating too much salt changes the good bugs in your gut. These angry bugs can make your body inflamed and your blood pressure rise. In mice, giving poop from salty-eaters to clean mice made the clean mice get high blood pressure too.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 520 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Ferguson JF, Aden LA, Barbaro NR, Van Beusecum JP, Xiao L, Simmons AJ, Warden C, Pasic L, Himmel LE, Washington MK, Revetta FL, Zhao S, Kumaresan S, Scholz MB, Tang Z, Chen G, Reilly MP, Kirabo A
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Claims (4)
Eating a lot of salt might change the balance of gut bacteria in both people and mice, increasing certain types that could raise the risk of heart problems.
Eating more salt might raise your blood pressure, especially if it changes the bacteria in your gut — which could be one way your diet affects heart health.
Eating too much salt might rev up the immune system in the guts and blood vessels of mice, leading to more inflammation and signs of immune cell activity.
If you take gut bacteria from mice that ate a lot of salt and put it into mice with no gut bacteria, those mice are more likely to get gut inflammation and high blood pressure — meaning bad changes in gut bugs from salt might spread disease risk.