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The Study

Adaptation of Muscles With Different Physiological Properties to Resistance Training With and Without Bloodflow Restriction

In simple terms

This study compared two kinds of leg workouts and found that both made people stronger and their calf muscle (soleus) bigger, but only the heavy lifting made one part of the calf (lateral gastrocnemius) grow. It doesn't prove one is better overall — just that they work differently in small ways.

54%

Analysis score

54/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting0
Methodology60
Publication100
Statistical54
Study type (basis of the score)
Randomized Controlled Trial
Level 1b - Individual RCT
What’s the bottom line?

This study tested if squeezing your thigh while doing light calf raises builds muscle like doing heavy calf raises.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Randomized Trials
Level 1b
54

54 / 100

Quality score

Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.

Can establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — you can get just as strong with light weights and blood flow restriction, but if you want to grow the outer calf muscle, you still need heavy weights.
  2. 2Both methods made legs 20–30% stronger.
  3. 3Both made the soleus (deep calf) muscle 12–15% bigger.
  4. 4Only heavy weights made the outer calf (lateral gastrocnemius) bigger (12%).
  5. 5The inner calf didn't grow at all.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Sports Health

Year

2026

Authors

Margarida Cidrais, C. Teodósio, Joana M. Correia, C. Vila-Chã, P. Pezarat-Correia, P. Bruno, Goncalo V. Mendonca

Open Access
Analysis v6

Related Content

Claims (6)

Assertion

Muscle growth occurs primarily due to mechanical tension during resistance training, while factors like metabolic stress, hormone changes, and muscle swelling do not play a major role.

Mechanistic
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Assertion

In untrained young adults, four weeks of heavy weight training increases the size of the lateral gastrocnemius muscle by about 12%, while low-weight training with restricted blood flow increases it by only 4%.

Quantitative
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Assertion

In untrained young adults, four weeks of either high-load or low-load resistance training with restricted blood flow increases the size of the soleus muscle by 12–15%.

Quantitative
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Assertion

In untrained young adults, two different types of strength training—lifting heavy weights and lifting light weights with restricted blood flow—produce the same amount of increase in leg strength after four weeks of five weekly sessions.

Causal
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Assertion

After four weeks of resistance training with restricted blood flow, whether using heavy or light weights, the size of the medial gastrocnemius muscle in untrained young adults does not increase significantly.

Descriptive
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Assertion

In untrained young adults, muscles in the calf grow more with heavy lifting than with blood-flow-restricted training, but strength increases equally in both cases, showing that muscle growth is not the main reason for early strength gains.

Mechanistic
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Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

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