Can a selenium pill help your eyes feel better if you have Graves’ disease?
Efficacy of selenium supplementation for mild-to-moderate Graves’ ophthalmopathy in a selenium-sufficient area (SeGOSS trial): study protocol for a phase III, multicenter, open-label, randomized, controlled intervention trial
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
People with mild eye problems from Graves’ disease took either a vitamin B pill or a vitamin B pill plus a selenium pill every day for 6 months to see if their eyes felt better.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 562 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
People with mild eye problems from Graves’ disease took either a vitamin B pill or a vitamin B pill plus a selenium pill every day for 6 months to see if their eyes felt better.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 562 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Authors
Chung CW, Jung KY, Jung EH, Lee MJ, Park YJ, Lee JK, Ahn HY, Cho SW
Related Content
Claims (4)
Taking 200 micrograms of sodium selenite daily for six months does not change the levels of thyroid autoantibodies in people with mild-to-moderate Graves’ ophthalmopathy who already have sufficient selenium.
In areas where people have adequate selenium levels, taking vitamin B complex supplements for six months does not significantly improve quality of life or reduce symptoms of mild-to-moderate Graves’ ophthalmopathy.
In adults with mild-to-moderate Graves’ eye disease living in areas with adequate selenium levels, taking 200 micrograms of sodium selenite daily for six months leads to more patients showing improvement in eye symptoms than taking vitamin B complex alone.
In areas where people have adequate selenium levels, taking selenium supplements with vitamin B complex for six months may result in a small reduction in eye inflammation symptoms for Graves’ ophthalmopathy, but the evidence is not conclusive because the study was not blinded.