The Study
Effects of plant-based diet (PBD) and exercise therapy (Ex) on weight and body composition in patients with primary hormone receptor (HR) positive breast cancer: A phase 2 randomized controlled trial.
This study showed that when women with breast cancer followed a special diet and exercise plan, they lost more weight than those who just got a treadmill and occasional calls. But it didn't prove that this diet stops cancer from coming back—it only looked at weight and body fat.
Analysis score
Maximum 90 for a randomized controlled trial.
Where the score came from
Women with breast cancer who ate plant-based meals and walked on a treadmill with help lost more weight and kept more muscle than those who just got a treadmill at home.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 561 / 100
Quality score
Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Losing 8 kg more weight and 4 kg more fat than the control group is a big difference for someone trying to improve health after cancer treatment.
- 2The group with diet and exercise lost 13% of their body weight and 6 kg of fat; the control group lost 5% weight and 2 kg fat.
- 3Muscle increased significantly in the diet/exercise group.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Journal of Clinical Oncology
Year
2024
Authors
Neil M. Iyengar, Erica Salehi, Jessica A Lavery, O. Chan, Sarah Lehman, M. Michalski, Gina A Fickera, Adele Carlson, Jenna Harrison, Whitney P. Underwood, Cara Anselmo, Su S Chun, Stephanie Cao, Catherine P. Lee, W. Demark-Wahnefried, C. Moskowitz, Lee W. Jones
Related Content
Claims (4)
Postmenopausal women with hormone receptor-positive breast cancer who followed a personalized plant-based diet and supervised exercise for 24 weeks gained more lean mass than those who received minimal attention.
Among postmenopausal women with hormone receptor-positive breast cancer taking hormone therapy, a personalized plant-based diet and supervised exercise led to 95% adherence to a weekly energy deficit in the first month and 64% adherence by the sixth month.
Postmenopausal women with hormone receptor-positive breast cancer on endocrine therapy who followed a personalized plant-based diet and supervised treadmill walking to create a 1,000 kcal weekly energy deficit lost 13% of their body weight and 6 kg of fat over 24 weeks, while those in a minimal attention control group lost 5% of their body weight and 2 kg of fat.
Higher energy expenditure from physical activity increases metabolic rate and improves the efficiency of achieving a caloric deficit.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.