The Study
Immunosuppressive therapy for the eye changes of Graves' disease.
This study looked at a few people who took a medicine for their eye problem and noticed their eyes didn't get better. But it didn't compare them to others who didn't take the medicine, so we can't say the medicine didn't work—maybe it just didn't help these specific people.
Analysis score
Maximum 58 for a case-control study.
Where the score came from
Doctors gave a drug called azathioprine to people with Graves' disease to calm their immune system and see if it helped their bulging eyes.
Where does this study sit?
Systematic Reviews & Meta-analyses
Max 100Randomized Trials
Max 90Cohort Studies
Max 72Case-Control
Max 58Cross-Sectional
Max 44Case Reports & Series
Max 30Expert Opinion
Max 526 / 100
Quality score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Even though the drug did what it was supposed to do (calm the immune system), it didn't help the eye problem, which means other causes might be behind the eye changes.
- 2The drug worked to suppress the immune system, but the eyes did not get better.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
The Journal of clinical endocrinology and metabolism
Year
1970
Authors
G. Burrow, M. Mitchell, R. Howard, L. Morrow
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.