Why trained athletes don't get as sore after hard workouts
Training Status Influences Regulation of Muscle and PBMC TLR4 Expression and Systemic Cytokine Responses to Vigorous Endurance Exercise
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
When you exercise hard, your body sends out warning signals — like a fire alarm. Trained people’s bodies learn to turn down the alarm so it doesn’t go off as loudly.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 553 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
When you exercise hard, your body sends out warning signals — like a fire alarm. Trained people’s bodies learn to turn down the alarm so it doesn’t go off as loudly.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 553 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Authors
Ducharme JB, Specht JW, Bailly AR, Fennel ZJ, Nava RC, Mermier CM, Laitano O, Deyhle MR