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The Study

Chronic Low-Calorie Sweetener Use and Risk of Abdominal Obesity among Older Adults: A Cohort Study

In simple terms

This study watched a group of older people for many years and noticed that those who drank diet soda or ate diet foods tended to gain more belly fat over time. But it didn't make people change what they ate—it just watched what they did. So we can't say the diet foods caused the weight gain—maybe people who were already gaining weight chose diet foods to try to lose weight.

59%

Analysis score

59/ 72

Maximum 72 for a cohort study.

Where the score came from

Reporting0
Methodology56
Publication100
Statistical77
Study type (basis of the score)
Cohort Study
Level 2b - Individual cohort study
What’s the bottom line?

This study looked at older people who drank diet drinks over many years and found they tended to gain more belly fat than those who didn't.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Cohort Studies
Level 2b
59

59 / 100

Quality score

Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — a 2.6 cm wider waist and 53% higher risk of belly fat buildup is meaningful for health, as abdominal obesity raises risk for heart disease and diabetes.
  2. 2People who used low-calorie sweeteners had 0.80 kg/m² higher BMI, 2.6 cm larger waist, 37% more abdominal obesity at any time, and 53% higher chance of developing it over 10 years.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

PLoS ONE

Year

2016

Authors

C. Chia, M. Shardell, Toshiko Tanaka, David Liu, Kristofer S. Gravenstein, E. Simonsick, J. Egan, L. Ferrucci

Open Access
71 citations
Analysis v5

Related Content

Claims (6)

Assertion

People who regularly consume low-calorie sweeteners tend to have more abdominal fat and larger waist measurements compared to those who do not.

Correlational
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Assertion

Older adults who regularly consume low-calorie sweeteners over 10 years have a 53% higher rate of developing abdominal obesity, measured by waist circumference above 102 cm for men and 88 cm for women, compared to those who do not, after accounting for initial weight, diet quality, and metabolic health.

Correlational
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Assertion

In adults aged 60 and older, long-term use of low-calorie sweeteners is linked to a 0.80 kg/m² increase in body mass index and a 2.6 cm increase in waist circumference over 10 years, even when accounting for diet, exercise, smoking, and metabolic health.

Correlational
Read analysis
Assertion

Older adults who regularly consume low-calorie sweeteners have a 37% higher rate of abdominal obesity compared to those who do not, even when accounting for their initial body fat, diet, and metabolic health.

Correlational
Read analysis
Assertion

Older adults who consume low-calorie sweeteners over time have a 53% higher rate of developing abdominal obesity compared to those who do not, even when accounting for their previous weight, diet quality, and metabolic health.

Correlational
Read analysis
Assertion

In older adults, consuming low-calorie sweeteners is linked to higher levels of abdominal fat, regardless of diet, exercise, smoking, or metabolic health status.

Correlational
Read analysis
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.