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The Study

The association of muscle weakness with functional disability in older patients with Diabetes mellitus: Measured by three different grip strength thresholds

In simple terms

This study took a snapshot of older patients with diabetes and looked at their grip strength and daily functioning at one point in time. It can show that weaker grip is linked to more difficulty with daily tasks, but it can't tell us if weak grip caused the problems or if both were caused by something else.

34%

Analysis score

34/ 44

Maximum 44 for a cross-sectional study.

Where the score came from

Reporting0
Methodology41
Publication100
Statistical0
Study type (basis of the score)
Cross-Sectional Study
Level 4 - Case series
What’s the bottom line?

Doctors wanted to know which way of measuring weak hand grip best shows if older people with diabetes will have trouble doing everyday things like dressing or cooking.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Cross-Sectional & Case Series
Level 4
34

34 / 100

Quality score

Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes, because catching people at risk early can help prevent falls and loss of independence, especially in older adults with diabetes who are already more vulnerable.
  2. 274% of older adults with diabetes had low grip strength using the regional norm.
  3. 3The cutoff of <35 kg for men and <20 kg for women found 98% of people without ADL disability (very few false negatives).
  4. 4All grip strength definitions linked to higher disability risk, but none were highly accurate at telling who had disability.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

PLOS ONE

Year

2025

Authors

S. Çavdar, F. Koçak, Sumru Savas

Open Access
5 citations
Analysis v5
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.