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The Study

A unique pseudo-eligibility analysis of longitudinal laboratory performance data from a transgender female competitive cyclist

In simple terms

This study is like watching one person do a science project on themselves over time. It shows what happened to their body during hormone treatment, but we can’t say for sure if the treatment caused the changes or if it would be the same for others. It’s interesting, but not strong proof.

24%

Analysis score

24/ 72

Maximum 72 for a cohort study.

Where the score came from

Reporting0
Methodology13
Publication100
Statistical0
Study type (basis of the score)
Cohort Study
Level 2b - Individual cohort study
What’s the bottom line?

A female cyclist who is transgender had her strength and fitness tested before and after one year of hormone treatment. Her muscle strength, jumping ability, and oxygen use went down after the treatment.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Cohort Studies
Level 2b
24

24 / 100

Quality score

Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes, the changes are meaningful because they show her physical performance got closer to typical female levels in some ways, but not all.
  2. 2Her handgrip strength dropped 7–13%, jumping ability dropped 23–29%, and oxygen use dropped 15–30%.
  3. 3Some of her results were better than average female cyclists, some were worse.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Translational Exercise Biomedicine

Year

2024

Authors

Blair R. Hamilton, Ke Hu, F. Guppy, Y. Pitsiladis

Open Access
4 citations
Analysis v5
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.