Simple DNA Test Estimates Your Age

Original Title

EpiAge: a next-generation sequencing-based ELOVL2 epigenetic clock for biological age assessment in saliva and blood across health and disease

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Summary

Scientists created a new test called EpiAgePublic that uses just 3 tiny markers on your DNA to guess how old your body really is (biological age) compared to your calendar age.

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Surprising Findings

Three markers outperform expectations

Scientists expected that hundreds of markers would be needed for accurate age prediction, but just three carefully chosen sites in the ELOVL2 gene achieved a correlation of 0.87 - matching much more complex models

Practical Takeaways

If you're a researcher, this simplified clock could make studies more cost-effective

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Publication

Journal

Aging (Albany NY)

Year

2025

Authors

D. Cheishvili, S. D. Carmo, Filippo Caraci, Margherita Grasso, Claudio Cuello, M. Szyf

Open Access
6 citations
Analysis v1