Does a longevity drug help older people feel better?
Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave an anti-aging drug called rapamycin to older adults once a week for a year to see if it made them healthier and safer.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 564 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave an anti-aging drug called rapamycin to older adults once a week for a year to see if it made them healthier and safer.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 564 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Authors
Moel M, Harinath G, Lee V, Nyquist A, Morgan SL, Isman A, Zalzala S
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Claims (6)
Taking rapamycin, even in small doses now and then, might increase the chance of getting serious infections like pneumonia in older people because it can weaken the immune system.
Taking a low weekly dose of a drug called rapamycin for a year might make older adults feel healthier overall, based on their own reports.
Taking a low weekly dose of a drug called rapamycin for a year might help older women build more lean muscle, which could slow down muscle loss as they age.
Taking a low weekly dose of a drug called rapamycin for a year might help reduce pain in healthy women over 50, based on how they reported feeling.
Taking rapamycin once a week for a year might be safe for healthy older adults, with no more side effects than a sugar pill — so it could be a candidate for slowing normal aging.