Taking a low weekly dose of a drug called rapamycin for a year might make older adults feel healthier overall, based on their own reports.

Taking rapamycin once a week for a year might be safe for healthy older adults, with no more side effects than a sugar pill — so it could be a candidate for slowing normal aging.

Taking a low weekly dose of a drug called rapamycin for a year might help reduce pain in healthy women over 50, based on how they reported feeling.

Taking low doses of a drug called rapamycin once a week doesn’t seem to reduce belly fat in healthy older adults after nearly a year, whether they take 5 mg or 10 mg — it’s about the same as taking a dummy pill.

Giving old mice the drug rapamycin less often (every 5 days instead of daily) at a specific dose helps them live longer without causing diabetes-like problems, showing that we might be able to get the good anti-aging effects without the bad side effects.

Scientists are trying different ways to reduce the bad side effects of a drug called rapamycin—like giving lower doses, combining it with other medicines, or taking breaks between doses—and recent findings suggest that taking breaks might help keep the good effects while reducing the bad ones.