Does insulin make your body store more fat than just lowering fat in the blood?
Adipose Tissue Free Fatty Acid Storage In Vivo: Effects of Insulin Versus Niacin as a Control for Suppression of Lipolysis
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 554 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 554 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Journal
Diabetes
Year
2015
Authors
Asem H. Ali, M. Mundi, C. Koutsari, D. Bernlohr, M. Jensen
Related Content
Claims (3)
When insulin levels rise, it reduces the breakdown of fat in fat cells by suppressing the enzyme hormone-sensitive lipase.
When insulin and niacin reduce fat breakdown to the same degree in healthy individuals, neither causes a greater increase in fat storage under the skin than the other, suggesting that insulin does not uniquely promote fat storage beyond what is expected from reduced fat breakdown.
In human fat tissue, neither insulin nor niacin strongly triggers the ERK1/2 signaling pathway under the conditions studied, indicating that this pathway likely does not play a major role in how free fatty acids are taken up by fat cells in the body.