Does a diabetes shot protect your eyes and kidneys?
Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A big study checked if a weekly diabetes medicine (exenatide) helps protect the eyes, kidneys, and heart in people with type 2 diabetes.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 582 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A big study checked if a weekly diabetes medicine (exenatide) helps protect the eyes, kidneys, and heart in people with type 2 diabetes.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 582 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Authors
Bethel MA, Mentz RJ, Merrill P, Buse JB, Chan JC, Goodman SG, Iqbal N, Jakuboniene N, Katona B, Lokhnygina Y, Lopes RD, Maggioni AP, Ohman P, Tankova T, Bakris GL, Hernandez AF, Holman RR
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Claims (6)
A diabetes drug made from Gila monster spit doesn't just help blood sugar — it can also help people lose weight, protect the heart, and even reduce cravings for things like alcohol or drugs.
Taking a weekly exenatide shot doesn’t really change how well your kidneys are working if you have type 2 diabetes — the numbers stayed about the same over time.
Taking a weekly exenatide shot doesn’t lower the chance of eye problems from diabetes, even if your blood sugar improves or you already had early eye issues.
Taking a weekly diabetes shot called exenatide doesn’t seem to lower the risk of a specific type of kidney problem in adults with type 2 diabetes — the numbers don’t show a clear benefit.
A weekly diabetes shot called exenatide doesn’t seem to lower the risk of serious kidney problems in adults with type 2 diabetes when looking at the raw data. But when researchers adjusted the numbers, it showed a small benefit when including a wider range of kidney issues, like high protein in the urine.