Does a diabetes shot protect your eyes and kidneys?
Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Exenatide didn’t reduce retinopathy risk despite lowering blood sugar
It’s long been assumed that better glycemic control reduces eye complications. This study challenges that idea, showing HbA1c lowering alone may not be enough.
Practical Takeaways
Don’t assume your diabetes medication protects your kidneys or eyes — ask your doctor about evidence for your specific drug.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Exenatide didn’t reduce retinopathy risk despite lowering blood sugar
It’s long been assumed that better glycemic control reduces eye complications. This study challenges that idea, showing HbA1c lowering alone may not be enough.
Practical Takeaways
Don’t assume your diabetes medication protects your kidneys or eyes — ask your doctor about evidence for your specific drug.
Publication
Journal
Diabetes Care
Year
2019
Authors
M. A. Bethel, R. Mentz, P. Merrill, J. Buse, J. Chan, Shaun G. Goodman, Shaun G. Goodman, N. Iqbal, Neli Jakubonienė, B. Katona, Y. Lokhnygina, R. Lopes, A. Maggioni, P. Öhman, T. Tankova, G. Bakris, Adrian F. Hernandez, R. Holman
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Claims (6)
A diabetes drug made from Gila monster spit doesn't just help blood sugar — it can also help people lose weight, protect the heart, and even reduce cravings for things like alcohol or drugs.
Taking a weekly exenatide shot doesn’t really change how well your kidneys are working if you have type 2 diabetes — the numbers stayed about the same over time.
Taking a weekly exenatide shot doesn’t lower the chance of eye problems from diabetes, even if your blood sugar improves or you already had early eye issues.
Taking a weekly diabetes shot called exenatide doesn’t seem to lower the risk of a specific type of kidney problem in adults with type 2 diabetes — the numbers don’t show a clear benefit.
A weekly diabetes shot called exenatide doesn’t seem to lower the risk of serious kidney problems in adults with type 2 diabetes when looking at the raw data. But when researchers adjusted the numbers, it showed a small benefit when including a wider range of kidney issues, like high protein in the urine.