Analysis Version
v1
History
Back to Study: Microvascular and Cardiovascular Outcomes Accordin...
quantitative
Analysis v1
Strong Support

Taking a weekly exenatide shot doesn’t really change how well your kidneys are working if you have type 2 diabetes — the numbers stayed about the same over time.

82
Pro
0
Against

Evidence from Studies

Supporting (1)

82

Community contributions welcome

82

Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial

Randomized Controlled Trial
Human
2020 Feb

The study looked at how once-weekly exenatide affects kidney function and found it doesn’t make a real difference in eGFR, just like the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial

Score: 82
DOI: 10.2337/dc19-1065

Similar Assertions

A weekly diabetes shot called exenatide doesn’t seem to lower the risk of serious kidney problems in adults with type 2 diabetes when looking at the raw data. But when researchers adjusted the numbers, it showed a small benefit when including a wider range of kidney issues, like high protein in the urine.

82
0
84%

For people with type 2 diabetes and healthy kidneys, taking a weekly exenatide shot might slightly lower the risk of heart problems or dying, but the evidence isn't strong and hasn't been fully checked for other factors.

82
0
81%

Taking a weekly diabetes shot called exenatide doesn’t seem to lower the risk of a specific type of kidney problem in adults with type 2 diabetes — the numbers don’t show a clear benefit.

82
0
77%

If you're overweight or obese and on a high-protein diet to lose weight, your kidneys stay just as healthy — or may even get a little better — even if you already have mild kidney issues, high blood pressure, or type 2 diabetes.

41
0
76%