Same brain protein in cows and people
Isolation and characterization of a cDNA clone coding for the calcium-binding subunit of calcineurin from bovine brain: an identical amino acid sequence to the human protein.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Bovine calcineurin B is identical to human calcineurin B at the amino acid level
Despite cows and humans diverging evolutionarily millions of years ago, this critical brain protein hasn’t changed at all — suggesting extreme functional constraint.
Practical Takeaways
Use bovine models to study human calcineurin B function with high confidence in biological relevance.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Bovine calcineurin B is identical to human calcineurin B at the amino acid level
Despite cows and humans diverging evolutionarily millions of years ago, this critical brain protein hasn’t changed at all — suggesting extreme functional constraint.
Practical Takeaways
Use bovine models to study human calcineurin B function with high confidence in biological relevance.
Publication
Journal
DNA sequence : the journal of DNA sequencing and mapping
Year
1994
Authors
Cheryl E. Nargang, D. Bottorff, K. Adachi
Related Content
Claims (4)
If a lab-made protein is almost exactly like one found in nature, experts might say it’s safe enough that it doesn’t need extra testing.
The brain protein calcineurin B in cows is exactly the same as the one in humans — letter for letter in its building blocks — which means it’s likely worked the same way for millions of years and could be studied across species.
Scientists figured out the full blueprint of a specific brain protein in cows, and it's made up of 841 genetic 'letters' arranged in three parts: a start section, the main instruction part, and an end section.
Humans and cows have almost identical DNA instructions for making a protein called calcineurin B — their blueprints match 97.1% in that section, which means it's super similar between the two species.