The Study
A Randomized Placebo-Controlled Crossover trial of Aloe Vera on Bioavailability of Vitamins C and B12, Blood Glucose, and Lipid Profile in Healthy Human Subjects
This study found that when people took aloe with vitamins, their vitamin levels went up — but we don’t know if the aloe really caused it, because we don’t know if the people or doctors knew who got what. So we can only say aloe and higher vitamin levels happened together, not that one made the other happen.
Analysis score
Maximum 90 for a randomized controlled trial.
Where the score came from
Scientists gave people aloe gel with vitamins and saw if the vitamins stayed in the blood longer.
Where does this study sit?
Systematic Reviews & Meta-analyses
Max 100Randomized Trials
Max 90Cohort Studies
Max 72Case-Control
Max 58Cross-Sectional
Max 44Case Reports & Series
Max 30Expert Opinion
Max 546 / 100
Quality score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1The increases were statistically significant but it's unclear if they make a big difference in health for most people.
- 2With aloe inner gel: vitamin C stayed higher for 24 hours, B12 spiked at 1-2 hours, antioxidants rose at 4 and 24 hours.
- 3With whole leaf gel: vitamin C higher at 4-6 hours, B12 spiked at 1-2 hours, antioxidants rose at 4 hours.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Journal Of Dietary Supplements
Year
2010
Authors
Jung-Mi Yun, Sital Singh, Rohan Jialal, Jason Rockwood, I. Jialal, S. Devaraj
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.