How belly hormones help control sugar and weight
Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Your gut makes special chemicals when you eat that tell your brain you're full and help your body use sugar better. Medicine based on these chemicals can help people with diabetes lose weight and stay healthier.
Surprising Findings
GIP, once thought to be less important in diabetes, may actually boost fat metabolism and insulin sensitivity when activated alongside GLP-1.
For years, scientists believed GIP was 'broken' in type 2 diabetes and not useful. Now, dual agonists like tirzepatide show GIP might be a key player when properly targeted.
Practical Takeaways
If you have type 2 diabetes or obesity and struggle with weight or heart risks, talk to your doctor about GLP-1 or dual agonist medications.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Your gut makes special chemicals when you eat that tell your brain you're full and help your body use sugar better. Medicine based on these chemicals can help people with diabetes lose weight and stay healthier.
Surprising Findings
GIP, once thought to be less important in diabetes, may actually boost fat metabolism and insulin sensitivity when activated alongside GLP-1.
For years, scientists believed GIP was 'broken' in type 2 diabetes and not useful. Now, dual agonists like tirzepatide show GIP might be a key player when properly targeted.
Practical Takeaways
If you have type 2 diabetes or obesity and struggle with weight or heart risks, talk to your doctor about GLP-1 or dual agonist medications.
Publication
Journal
Frontiers in Endocrinology
Year
2024
Authors
Q. Liu
Related Content
Claims (2)
Some diabetes and weight-loss drugs, like tirzepatide, can help people lose a lot of weight—up to nearly 18% more than a fake treatment over a year and a half—especially in those without diabetes, and they might also improve overall health.
Some diabetes drugs like liraglutide, semaglutide, and dulaglutide may help protect the heart and lower the chance of serious heart problems in people with type 2 diabetes who already have heart disease — and this benefit might not just be because they lower blood sugar.