Nasal Spray Helps Cold Symptoms
Povidone-iodine nasal spray (Nasodine®) for the common cold: a randomized, controlled, double-blind, Phase III clinical trial
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 572 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 572 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Journal
Frontiers in Medicine
Year
2025
Authors
Thomas M. Polasek, Peter L. Friedland
Related Content
Claims (5)
This says that a nasal spray called Nasodine helps people with colds feel better in their daily lives. It claims that using Nasodine makes people 16% more comfortable compared to using a simple saltwater spray.
Nasodine is a medicine that's easy for adults to use. Some people get a little bit of nose discomfort that goes away quickly, but it doesn't cause any serious problems.
Using a povidone-iodine nose spray four times a day for 5 days might help reduce how bad a common cold feels by about 12.6% compared to a saltwater spray, but the results weren't quite strong enough to be sure.
If you take Nasodine medicine soon after you start feeling sick with a cold, it can make your symptoms much less severe. Getting treated early is really important for it to work well.
Using Nasodine spray doesn't really shorten how long a common cold lasts—it takes about 10 days to get better, just like using a simple saltwater spray.