What are the biggest breakthroughs in brain ultrasound?
A scientometric analysis of the 100 most cited articles on magnetic resonance guided focused ultrasound
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The #1 most-cited paper is an animal study from 2001—not a human trial.
Most assume breakthrough medical tech is driven by human clinical trials, but here, a rabbit experiment has had more influence than any human study.
Practical Takeaways
If you or a loved one has essential tremor, ask your neurologist about MRgFUS thalamotomy—it’s FDA-approved, noninvasive, and backed by top-tier evidence.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The #1 most-cited paper is an animal study from 2001—not a human trial.
Most assume breakthrough medical tech is driven by human clinical trials, but here, a rabbit experiment has had more influence than any human study.
Practical Takeaways
If you or a loved one has essential tremor, ask your neurologist about MRgFUS thalamotomy—it’s FDA-approved, noninvasive, and backed by top-tier evidence.
Publication
Journal
Frontiers in Human Neuroscience
Year
2022
Authors
K. Garg, M. Ranjan, V. Krishna, Manmohanjit Singh, A. Rezai
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Claims (6)
Two universities — Toronto and Virginia — have written the most popular science papers on a type of medical technology called MRgFUS, with Toronto writing 28 and Virginia writing 15 of the top 100 most-read papers.
The U.S. and Canada together produced more than half of the most talked-about scientific papers on a special type of ultrasound therapy used in medicine.
A medical journal called the Journal of Neurosurgery published more of the most popular MRgFUS research papers than any other journal, while two other journals, Radiology and the New England Journal of Medicine, had papers that got read and cited way more times overall.
A famous 2001 study on rabbits used sound waves and MRI to temporarily open the brain’s protective barrier, letting drugs in without surgery — and this became the go-to method for brain drug delivery research.
Scientists have written the most papers about using MRgFUS to open the brain’s protective barrier and to treat movement problems like tremors — and when they study it in people, they’re mostly looking at essential tremor.