Chocolate Chemical Stops Fitness Gains?

Original Title

(–)-Epicatechin Supplementation Inhibits Aerobic Adaptations to Cycling Exercise in Humans

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Summary

This study tested if a chemical from dark chocolate helps people get fitter when they bike for 4 weeks.

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Surprising Findings

(–)-epicatechin blocked aerobic and mitochondrial adaptations despite being linked to improved fitness in animal studies.

Previous rodent research showed (–)-epicatechin boosted mitochondrial biogenesis and exercise performance, so it was expected to enhance human training—but instead, it appeared to blunt key improvements.

Practical Takeaways

Skip (–)-epicatechin supplements if your goal is to improve endurance or aerobic fitness through training.

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