Can a special magnesium pill make your brain younger and help you sleep better?
The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave people a special magnesium pill for 6 weeks to see if it helped their brain work better and sleep more restfully.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 575 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave people a special magnesium pill for 6 weeks to see if it helped their brain work better and sleep more restfully.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 575 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
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Claims (6)
In adults aged 18–45 with poor sleep, taking 2 grams of magnesium L-threonate daily for 6 weeks leads to a greater reduction in self-reported sleep problems than a placebo, but does not change sleep measurements from wearable devices.
Taking magnesium supplements leads to better sleep quality through changes in brain chemicals that control sleep.
In healthy adults aged 18–45 with self-reported poor sleep, taking 2 grams of magnesium L-threonate daily for 6 weeks leads to an 8.4-point increase in overall cognitive performance on the NIH Total Cognition Composite, compared to a 5.6-point increase in those taking a placebo.
In adults aged 18–45 with self-reported poor sleep, taking 2 grams of magnesium L-threonate daily for six weeks is associated with a 7.5-year reduction in estimated cognitive age compared to placebo, indicating a statistically significant improvement in cognitive performance relative to age-matched norms.
Adults aged 18–45 with poor sleep who took 2 grams of magnesium L-threonate daily for 6 weeks showed a 6.3% improvement in reaction time and visuo-motor coordination on the 3D Aim Trainer, while those taking a placebo showed no significant change.