Did the medicine help girls grow taller than their parents' genes predicted?
Surpassing genetic height potential at final adult height after monthly depot leuprolide therapy in Taiwanese girls with central precocious or early puberty: a ROC-based analysis
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Over half of the girls surpassed their genetically predicted height despite having early puberty, which typically reduces final height.
Early puberty usually leads to shorter adult height because bones mature too quickly. The fact that 53.4% exceeded mid-parental height challenges the assumption that early puberty always limits growth potential when treated.
Practical Takeaways
For families considering GnRHa therapy for central precocious puberty, earlier initiation may improve the chance of exceeding genetic height potential.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Over half of the girls surpassed their genetically predicted height despite having early puberty, which typically reduces final height.
Early puberty usually leads to shorter adult height because bones mature too quickly. The fact that 53.4% exceeded mid-parental height challenges the assumption that early puberty always limits growth potential when treated.
Practical Takeaways
For families considering GnRHa therapy for central precocious puberty, earlier initiation may improve the chance of exceeding genetic height potential.
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Related Content
Claims (4)
Giving certain hormone treatments to girls who start puberty too early can help them grow taller as adults.
Taiwanese girls with early puberty who got monthly shots of a drug called leuprolide were more likely to grow taller than their parents' predicted height, especially if they started treatment younger and had more advanced bone growth.
Girls in Taiwan who start a certain puberty-delaying treatment earlier might end up taller as adults, especially if they start young enough to grow past their parents' expected height — but we can't say for sure what exactly causes the difference.
Taiwanese girls with early puberty who keep growing well while on monthly leuprolide shots are more likely to end up taller than their parents' height would predict — by about 6.5 cm on average.