Taiwanese girls with early puberty who keep growing well while on monthly leuprolide shots are more likely to end up taller than their parents' height would predict — by about 6.5 cm on average.

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Pro

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Against

Evidence from Studies

Supporting (1)

36

Community contributions welcome

36

Surpassing genetic height potential at final adult height after monthly depot leuprolide therapy in Taiwanese girls with central precocious or early puberty: a ROC-based analysis

Cohort Study

Human

The study looked at the same treatment and girls as described in the claim, and found that those who grew faster during treatment ended up taller than their parents’ height predicted, by about 6.57 cm.

Contradicting (0)

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No contradicting evidence found

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Source Study

Surpassing genetic height potential at final adult height after monthly depot leuprolide therapy in Taiwanese girls with central precocious or early puberty: a ROC-based analysis

Score: 36

DOI: 10.3389/fped.2026.1819205

Similar Assertions

Girls in Taiwan who start a certain puberty-delaying treatment earlier might end up taller as adults, especially if they start young enough to grow past their parents' expected height — but we can't say for sure what exactly causes the difference.

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Taiwanese girls with early puberty who got monthly shots of a drug called leuprolide were more likely to grow taller than their parents' predicted height, especially if they started treatment younger and had more advanced bone growth.

36

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Girls with early puberty who get both a hormone blocker and growth hormone end up taller than expected—about 9 cm more—compared to those who only get the hormone blocker, which helps about 5 cm.

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For girls with early puberty who are treated with two hormones (one for puberty and one for growth), the ones who grow more during treatment tend to have started with a lower predicted adult height and more mature bones. How long or how much growth hormone they take doesn’t seem to affect how much they grow.

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50

71%

Girls with early puberty who get a combo of two treatments don't end up taller as adults than those who get just one treatment, even though the combo helps them grow more during treatment.

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