How Lifting Weights Changes Muscles Inside
Myofibril and Mitochondrial Area Changes in Type I and II Fibers Following 10 Weeks of Resistance Training in Previously Untrained Men
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Mitochondrial measurements disagreed between methods
Histology showed mitochondrial growth while biochemical assays showed no change - scientists can't agree on how to measure cellular changes
Practical Takeaways
Track muscle density changes with pQCT scans instead of biopsies
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Mitochondrial measurements disagreed between methods
Histology showed mitochondrial growth while biochemical assays showed no change - scientists can't agree on how to measure cellular changes
Practical Takeaways
Track muscle density changes with pQCT scans instead of biopsies
Publication
Journal
Frontiers in Physiology
Year
2021
Authors
Bradley A Ruple, Joshua S Godwin, Paulo H. C. Mesquita, Shelby C. Osburn, C. Sexton, Morgan A Smith, Jeremy C. Ogletree, Michael D. Goodlett, Joseph L. Edison, A. Ferrando, A. Frugé, A. Kavazis, Kaelin C. Young, M. Roberts
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Claims (6)
When scientists measure changes in muscle cells after strength training using two different methods, the results don't match up well - so they should be looked at separately rather than compared directly.
When young guys who haven't lifted weights before do strength training for 10 weeks, their muscle fibers grow in a way that makes them stronger, not just bigger with extra fluid. It's like building real muscle instead of just puffing it up.
When young guys who don't exercise start lifting weights for 10 weeks, the energy-producing parts inside their muscles grow faster than the muscles themselves.
When untrained young men do strength training, a special scan called pQCT can show changes in muscle density that match changes in muscle fiber size, suggesting this scan might help track muscle growth without surgery.
In young men who don't exercise, slow-twitch muscle fibers have more energy-producing parts than fast-twitch fibers to start with, and even after 10 weeks of weight training—which boosts these parts overall—the slow-twitch ones still keep their lead.