How Fish Oil Helps Your Heart
The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
EPA and DHA may activate the Nrf2 pathway by interacting with Keap1—turning on the body’s master antioxidant switch.
Most people assume antioxidants come from vitamins (C, E), but here, fats themselves trigger the body’s own defense system at the genetic level.
Practical Takeaways
Get your omega-3 index tested (via blood spot test) and aim for >8%—most people are under 4%.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
EPA and DHA may activate the Nrf2 pathway by interacting with Keap1—turning on the body’s master antioxidant switch.
Most people assume antioxidants come from vitamins (C, E), but here, fats themselves trigger the body’s own defense system at the genetic level.
Practical Takeaways
Get your omega-3 index tested (via blood spot test) and aim for >8%—most people are under 4%.
Publication
Journal
Biomedicines
Year
2020
Authors
F. Oppedisano, R. Macrì, M. Gliozzi, V. Musolino, C. Carresi, J. Maiuolo, F. Bosco, S. Nucera, Maria Caterina Zito, Lorenza Guarnieri, F. Scarano, Caterina Nicita, A. Coppoletta, S. Ruga, M. Scicchitano, R. Mollace, E. Palma, V. Mollace
Related Content
Claims (8)
Eating fish or fish oil rich in EPA and DHA omega-3s may help make dangerous fatty buildups in your arteries more stable and less likely to burst, by calming down harmful inflammation and helping your blood vessels relax better.
People with more of the good omega-3 fats (EPA and DHA) in their red blood cells tend to have less heart disease and do better over time if they already have heart problems.
Taking fish oil supplements with EPA and DHA might help keep your blood from clotting too easily, which could lower your chance of having a heart attack or stroke if you already have heart disease.
Taking fish oil supplements (EPA and DHA) may help your heart cells fight off damage during heart attacks by boosting a natural antioxidant shield and reducing harmful fat breakdown.
Omega-3 fats from fish can turn into natural chemicals that help your body calm down inflammation after a heart attack or when arteries are clogged, which helps heal the damage and shrink the plaques.