Study analysis · Behavioral Sciences · 2026
Your hormones might be deciding whether you risk your own money for charity—and the stress hormone cortisol might be the real hero.
Men with more testosterone take bigger risks, even to help others, but men with more stress hormone cortisol play it safe—especially when helping others, and the two hormones don't interact as previously thought.
Overview
What the study found
The study in plain English — the bottom line, every takeaway we extracted, and what to do with them.
In simple terms
This study is like taking a snapshot at one moment. The scientists measured hormones and behavior at the same time, so they can see if they happen together, but they can't tell if one causes the other. It's like seeing that people who carry umbrellas are more likely to have rain outside, but carrying an umbrella doesn't cause rain.
What’s the bottom line?
We wanted to see if natural testosterone and cortisol levels in men affect whether they take risks to help others. We played a game where they could gamble to win money for themselves or a charity.
How strong is this study?
The study was well-planned in some ways: they decided how many people to include ahead of time, used a careful task, and collected samples at the same time of day. But they had only a small group of men and took hormone samples just once, so the results might not be very reliable.
40 / 100
- COI disclosure+40/40
- Data availabilitydata not shared
- Code availabilitycode not shared
7 / 100
- Randomizationnot randomized
- Blindingnot blinded
- Control groupno control group
- Sample size (n=69)+5.8/20
- Follow-upno follow-up reported
100 / 100
77 / 100
- P-values+15/15
- Effect size+20/20
- Confidence intervals+15/15
- Pre-registrationnot pre-registered
Each component is scored out of 100 and then capped by the study design — a case series cannot reach the ceiling a randomised trial can, however well it is reported.
Where it sits
RCT reviewsReviews of RCTs (Meta-analyses)
Max 100Randomized TrialsRandomized Trials
Max 90Reviews of Cohort StudiesReviews of Cohort Studies
Max 85Cohort StudiesCohort Studies
Max 72Reviews of Case-Control StudiesReviews of Case-Control Studies
Max 63Case-Control StudiesCase-Control Studies
Max 58Cross-Sectional & Case SeriesCross-Sectional & Case Series
Max 50Expert OpinionExpert Opinion
Max 544 / 100
Probability of being correct
Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.
This design cannot establish causation — the findings describe an association, not a cause. This is a cross-sectional observational study without randomization or a control group. Hormone levels and risk-taking behavior were measured at the same time, making it impossible to determine whether hormones influence behavior or if the relationship is due to other factors. No causal conclusions can be drawn.
No Conflicts
No conflicts of interest identified
No conflicts of interest or funding sources are disclosed in the provided text; the study appears to be an independent academic investigation without industry ties.
The text is truncated, and no explicit conflict of interest or funding statement is visible. The study appears to be academic in nature, but without full text, confirmation is limited.
Key takeaways
- 01
Men with more testosterone took more risks in both cases.
- 02
Men with more cortisol took fewer risks, especially when playing for charity.
- 03
There was no sign that testosterone and cortisol worked together.
- 04
The effects were small but measurable.
- 05
Testosterone seemed to increase risk-taking generally, while cortisol reduced it, particularly for altruistic risks.
Surprising findings
- Higher testosterone was positively associated with prosocial risk-taking, meaning men with more testosterone were more willing to risk money for charity, not just for themselves.Common belief is that testosterone fuels egoistic, self-serving behavior. Here, it also promotes altruistic risk-taking, suggesting a link to status-seeking through heroism.
- The dual-hormone hypothesis was not supported: no testosterone-cortisol interaction was found.Many studies and theories suggest cortisol moderates testosterone's effects, but this study found they work independently, at least in this task.
- Cortisol's inhibitory effect on risk-taking was stronger in the prosocial condition than in the self-oriented condition.You'd think stress hormones might make you more cautious overall, but here the suppression was especially pronounced when the risk was to benefit others, not yourself.
Practical takeaways
If you're planning a charitable campaign or crowdfunding, consider that people are more risk-averse when donating. De-emphasize risk (e.g., 'guaranteed impact') and reduce perceived personal loss to encourage donations.
Study is correlational and only on young men, so individual differences vary.
medium confidenceFor personal risk-taking: understand that your cortisol levels (stress) may make you overly cautious, especially in high-stakes or altruistic situations. Manage stress to avoid missing opportunities for prosocial risk-taking.
This doesn't mean you should ignore risks – it's about balance.
medium confidenceWhen designing risk-related tasks or games (e.g., fundraising games), note that men with higher testosterone are more likely to take risks when stakes are high. You might tailor messaging accordingly, but be careful about stereotyping.
The effect was modest and context-dependent.
low confidenceWhy this study matters
Testosterone: The Risk-Taking Hormone
In a study of 69 healthy young men, those with higher baseline testosterone were more likely to gamble for both personal gains and charity donations. For every unit increase in testosterone, risk-taking increased by about 35% (b=0.353, p=0.077). This effect was strongest when the stakes were high – specifically when the probability of loss was high relative to gain. Interestingly, testosterone didn't differentiate between playing for yourself or for a charity.
Most people think testosterone only drives selfish or aggressive behavior, but here it also promotes altruistic risk-taking, just by boosting general risk appetite.
Cortisol: The Brake on Heroism
Higher cortisol levels were associated with lower risk-taking, and this was especially true in the prosocial condition (where benefits go to charity). For a given increase in cortisol, risk-taking dropped by about 1.2 units overall (b=-1.224, p=0.086), but under prosocial conditions, the effect was much stronger (b=-2.057, p=0.004).
This suggests that stress hormones might make us more cautious about risking our own resources for others, potentially explaining why people sometimes fail to act altruistically under stress.
The Dual-Hormone Hypothesis Fails Again
The study found no significant interaction between testosterone and cortisol (p=0.638), meaning they act independently, not as a team. This contradicts the popular 'dual-hormone hypothesis' which suggests cortisol moderates testosterone's effects on status-seeking behavior.
This adds to a growing body of evidence that the interplay between these hormones is context-dependent and not as straightforward as once believed.
People Are Less Risk-Taking When Playing for Charity
Across the board, participants took fewer risks when the gains would go to a charity rather than themselves (b=-0.134, p=0.080). This effect was more pronounced at higher loss-to-gain ratios, meaning when the gamble was riskier, people were especially cautious about risking money for others.
This challenges the idea that people are more adventurous when playing with 'other people's money' – here, they were more conservative when the beneficiary was a charity.
High Stakes Amplify Hormonal Effects
Both testosterone's risk-promoting effect and cortisol's risk-suppressing effect were stronger when the odds were more unfavorable (i.e., high loss-to-gain ratio). For instance, testosterone's effect was significant at moderate and high risk levels but not at low risk levels (p=0.202 at low). Similarly, cortisol's dampening effect was strongest at high loss ratios.
This suggests that hormonal influences on risk-taking are not constant but are amplified in challenging situations, which might explain why some people crack under pressure while others thrive.
Want the whole report?
Detailed mode opens the full scientific breakdown — every score component, the methodology, conflicts of interest, the evidence analysis behind each claim, and the raw study data.
Overview
What the study found
The study in plain English — the bottom line, every takeaway we extracted, and what to do with them.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
We wanted to see if natural testosterone and cortisol levels in men affect whether they take risks to help others. We played a game where they could gamble to win money for themselves or a charity.
Research results
Men with more testosterone took more risks in both cases. Men with more cortisol took fewer risks, especially when playing for charity. There was no sign that testosterone and cortisol worked together.
What this means - more context
The effects were small but measurable. Testosterone seemed to increase risk-taking generally, while cortisol reduced it, particularly for altruistic risks.
To examine the association between endogenous testosterone and prosocial risk-taking and whether cortisol moderates this relationship.
In a sample of 69 healthy young men, higher endogenous testosterone was positively associated with risk-taking in both self-oriented and prosocial contexts, while higher cortisol was negatively associated, with a stronger inhibitory effect in the prosocial condition. No testosterone-cortisol interaction was found, failing to support the dual-hormone hypothesis.
Methods Used
Cross-sectional study; 69 healthy males (mean age 21.44) completed an adapted probabilistic gambling task with self and prosocial conditions. Saliva samples measured basal testosterone and cortisol. Generalized linear mixed models (GLMM) analyzed predictors of risk-taking choices.
Main Finding
Testosterone positively predicted risk-taking (b=0.353, p=0.077), cortisol negatively predicted risk-taking (b=-1.224, p=0.086), and these effects were stronger at higher loss-to-gain ratios. Cortisol's suppression was more pronounced in the prosocial condition. No significant testosterone-cortisol interaction.
Confidence Level
Moderate: small sample, correlational design, single hormone measurement, but significant effects and interactions support findings.
Study Flags
Red Flags
- •Small sample size (n=69)
- •Correlational design - causal inference limited
- •Single saliva sample for hormone measurement
Surprising Findings
Higher testosterone was positively associated with prosocial risk-taking, meaning men with more testosterone were more willing to risk money for charity, not just for themselves.
Common belief is that testosterone fuels egoistic, self-serving behavior. Here, it also promotes altruistic risk-taking, suggesting a link to status-seeking through heroism.
Practical Takeaways
If you're planning a charitable campaign or crowdfunding, consider that people are more risk-averse when donating. De-emphasize risk (e.g., 'guaranteed impact') and reduce perceived personal loss to encourage donations.
RCT reviewsReviews of RCTs (Meta-analyses)
Max 100Randomized TrialsRandomized Trials
Max 90Reviews of Cohort StudiesReviews of Cohort Studies
Max 85Cohort StudiesCohort Studies
Max 72Reviews of Case-Control StudiesReviews of Case-Control Studies
Max 63Case-Control StudiesCase-Control Studies
Max 58Cross-Sectional & Case SeriesCross-Sectional & Case Series
Max 50Expert OpinionExpert Opinion
Max 544 / 100
Probability of being correct
Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.
Human Cross-Sectional
Subject
Moderate probability
on the GRADE evidence scale
This study is like taking a snapshot at one moment. The scientists measured hormones and behavior at the same time, so they can see if they happen together, but they can't tell if one causes the other. It's like seeing that people who carry umbrellas are more likely to have rain outside, but carrying an umbrella doesn't cause rain.
The study has a COI section but no disclosure was found. A small penalty has been applied.
Strengths
- A priori sample size calculation
- Counterbalanced task order (ABBA design)
- Saliva samples collected at consistent times to control for circadian rhythm
Weaknesses
- Cross-sectional design prevents causal inference
- Small sample size (n=69)
- Single saliva sample may not reliably reflect basal hormone levels
Methodology
Evidence Keywords
Statistical Reporting
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
We wanted to see if natural testosterone and cortisol levels in men affect whether they take risks to help others. We played a game where they could gamble to win money for themselves or a charity.
Research results
Men with more testosterone took more risks in both cases. Men with more cortisol took fewer risks, especially when playing for charity. There was no sign that testosterone and cortisol worked together.
What this means - more context
The effects were small but measurable. Testosterone seemed to increase risk-taking generally, while cortisol reduced it, particularly for altruistic risks.
To examine the association between endogenous testosterone and prosocial risk-taking and whether cortisol moderates this relationship.
In a sample of 69 healthy young men, higher endogenous testosterone was positively associated with risk-taking in both self-oriented and prosocial contexts, while higher cortisol was negatively associated, with a stronger inhibitory effect in the prosocial condition. No testosterone-cortisol interaction was found, failing to support the dual-hormone hypothesis.
Methods Used
Cross-sectional study; 69 healthy males (mean age 21.44) completed an adapted probabilistic gambling task with self and prosocial conditions. Saliva samples measured basal testosterone and cortisol. Generalized linear mixed models (GLMM) analyzed predictors of risk-taking choices.
Main Finding
Testosterone positively predicted risk-taking (b=0.353, p=0.077), cortisol negatively predicted risk-taking (b=-1.224, p=0.086), and these effects were stronger at higher loss-to-gain ratios. Cortisol's suppression was more pronounced in the prosocial condition. No significant testosterone-cortisol interaction.
Confidence Level
Moderate: small sample, correlational design, single hormone measurement, but significant effects and interactions support findings.
Study Flags
Red Flags
- •Small sample size (n=69)
- •Correlational design - causal inference limited
- •Single saliva sample for hormone measurement
Surprising Findings
Higher testosterone was positively associated with prosocial risk-taking, meaning men with more testosterone were more willing to risk money for charity, not just for themselves.
Common belief is that testosterone fuels egoistic, self-serving behavior. Here, it also promotes altruistic risk-taking, suggesting a link to status-seeking through heroism.
Practical Takeaways
If you're planning a charitable campaign or crowdfunding, consider that people are more risk-averse when donating. De-emphasize risk (e.g., 'guaranteed impact') and reduce perceived personal loss to encourage donations.
RCT reviewsReviews of RCTs (Meta-analyses)
Max 100Randomized TrialsRandomized Trials
Max 90Reviews of Cohort StudiesReviews of Cohort Studies
Max 85Cohort StudiesCohort Studies
Max 72Reviews of Case-Control StudiesReviews of Case-Control Studies
Max 63Case-Control StudiesCase-Control Studies
Max 58Cross-Sectional & Case SeriesCross-Sectional & Case Series
Max 50Expert OpinionExpert Opinion
Max 544 / 100
Probability of being correct
Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.
Human Cross-Sectional
Subject
Moderate probability
on the GRADE evidence scale
This study is like taking a snapshot at one moment. The scientists measured hormones and behavior at the same time, so they can see if they happen together, but they can't tell if one causes the other. It's like seeing that people who carry umbrellas are more likely to have rain outside, but carrying an umbrella doesn't cause rain.
The study has a COI section but no disclosure was found. A small penalty has been applied.
Strengths
- A priori sample size calculation
- Counterbalanced task order (ABBA design)
- Saliva samples collected at consistent times to control for circadian rhythm
Weaknesses
- Cross-sectional design prevents causal inference
- Small sample size (n=69)
- Single saliva sample may not reliably reflect basal hormone levels
Methodology
Evidence Keywords
Statistical Reporting
Scoring
How strong is this study?
The study was well-planned in some ways: they decided how many people to include ahead of time, used a careful task, and collected samples at the same time of day. But they had only a small group of men and took hormone samples just once, so the results might not be very reliable.
40 / 100
- COI disclosure+40/40
- Data availabilitydata not shared
- Code availabilitycode not shared
7 / 100
- Randomizationnot randomized
- Blindingnot blinded
- Control groupno control group
- Sample size (n=69)+5.8/20
- Follow-upno follow-up reported
100 / 100
77 / 100
- P-values+15/15
- Effect size+20/20
- Confidence intervals+15/15
- Pre-registrationnot pre-registered
Each component is scored out of 100 and then capped by the study design — a case series cannot reach the ceiling a randomised trial can, however well it is reported.
Where it sits
RCT reviewsReviews of RCTs (Meta-analyses)
Max 100Randomized TrialsRandomized Trials
Max 90Reviews of Cohort StudiesReviews of Cohort Studies
Max 85Cohort StudiesCohort Studies
Max 72Reviews of Case-Control StudiesReviews of Case-Control Studies
Max 63Case-Control StudiesCase-Control Studies
Max 58Cross-Sectional & Case SeriesCross-Sectional & Case Series
Max 50Expert OpinionExpert Opinion
Max 544 / 100
Probability of being correct
Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.
This design cannot establish causation — the findings describe an association, not a cause. This is a cross-sectional observational study without randomization or a control group. Hormone levels and risk-taking behavior were measured at the same time, making it impossible to determine whether hormones influence behavior or if the relationship is due to other factors. No causal conclusions can be drawn.
No Conflicts
No conflicts of interest identified
No conflicts of interest or funding sources are disclosed in the provided text; the study appears to be an independent academic investigation without industry ties.
The text is truncated, and no explicit conflict of interest or funding statement is visible. The study appears to be academic in nature, but without full text, confirmation is limited.