The Study
Anti-Aging Effects of Low-Molecular-Weight Collagen Peptide Supplementation on Facial Wrinkles and Skin Hydration: Outcomes from a Six-Week Randomized, Double-Blind, Placebo-Controlled Trial
This study is like a fair test where half the women took a special pill and half took a sugar pill, and scientists measured their skin with fancy tools. They found the pill group had less wrinkles and more moisture — so we can say the pill probably helped with those things. But we can't say it makes you younger overall.
Analysis score
Maximum 45 for a randomized controlled trial.
Where the score came from
This study tested if taking a daily collagen drink for 6 weeks helps reduce wrinkles and dry skin in middle-aged women.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 545 / 100
Quality score
Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Yes — these changes are large enough to be seen and felt by the women themselves, with 90% reporting high satisfaction.
- 2Women who took collagen had 46% fewer wrinkles, 44% smaller wrinkle areas, and 34% more skin moisture — while those on placebo saw no change.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Cosmetics
Year
2024
Authors
Juan Antonio Carrillo-Norte, Baldomero García-Mir, Lluis Quintana, Bruno Buracchio, Rafael Guerrero-Bonmatty
Related Content
Claims (6)
Taking 2.5 grams of low-molecular-weight collagen peptides daily for six weeks increases skin hydration by 34% in healthy women aged 30–65, as measured by corneometry, compared to a placebo.
In a six-week study, 90% of women who took 2.5 grams of low-molecular-weight collagen peptides daily reported high satisfaction with improved skin hydration and reduced wrinkles, and these reports matched objective measurements of skin changes.
Taking collagen peptide supplements by mouth increases skin hydration and elasticity in humans.
Taking 2.5 grams of low-molecular-weight collagen peptides daily for six weeks reduces facial wrinkle volume by 46% and wrinkle area by 44% in healthy women aged 30–65 with moderate to severe crow’s feet wrinkles, as measured by biometric imaging.
Taking 2.5 grams of low-molecular-weight collagen peptides daily for six weeks does not cause adverse events in healthy women aged 30 to 65.
Taking 2.5 grams of low-molecular-weight collagen peptides daily for six weeks does not change skin firmness or elasticity in healthy women aged 30 to 65, according to measurements taken with a Cutometer device.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.