Fungi Make Medicine-Like Stuff

Original Title

Bioactive Compounds from Terrestrial and Marine-Derived Fungi of the Genus Neosartorya

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Summary

Tiny fungi, especially ones called Neosartorya, can make special chemicals that might help fight diseases like cancer, infections, and heart problems.

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Surprising Findings

A fungal compound matched real antibiotics in killing drug-resistant bacteria.

ESBL-producing E. coli is a dangerous superbug resistant to most antibiotics, yet 5,6-dimethoxycircumdatin C had an MIC of 2.0 μg/mL — comparable to clinical antibiotics.

Practical Takeaways

Support conservation of diverse ecosystems — they may harbor undiscovered medicinal fungi.

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Publication

Journal

Molecules

Year

2022

Authors

Joana D. M. de Sá, D. Kumla, T. Dethoup, A. Kijjoa

Open Access
19 citations
Analysis v1