Effects of 12 Weeks of Hypertrophy Resistance Exercise Training Combined with Collagen Peptide Supplementation on the Skeletal Muscle Proteome in Recreationally Active Men

In young men undergoing 12 weeks of muscle-building resistance training, taking collagen peptide supplements leads to a fivefold increase in the production of specific muscle proteins involved in contractile function, such as myosin and Z-disk components, compared to those taking a placebo.

In young men who exercise recreationally, taking 15 grams of collagen peptides daily along with a 12-week strength training program results in greater gains in muscle mass and more changes in muscle proteins than strength training alone with a placebo.

Taking collagen supplements does not help muscles grow larger if you are already consuming enough total protein and vitamin C, because collagen does not contain the right amino acids or biological mechanism to directly stimulate muscle growth.

Taking collagen peptides while doing strength training leads to specific changes in muscle cells that support muscle function and repair, whereas taking a placebo during the same training only triggers general metabolic changes.

Taking collagen peptides while doing strength training does not lead to greater increases in maximum strength in young men compared to strength training alone, even though it may increase muscle mass and protein markers.