How a once-a-week shot helps people lose weight and protect their heart
Semaglutide as a GLP-1 Agonist: A Breakthrough in Obesity Treatment
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The oral version of semaglutide (50 mg daily) achieved nearly the same weight loss as the injectable version.
Most people assume injections are always more effective than pills—this shows a daily pill can match a weekly shot, which could revolutionize accessibility and reduce stigma.
Practical Takeaways
If you’re obese with a comorbidity (like prediabetes or high blood pressure), talk to your doctor about semaglutide as a tool—not a replacement—for lifestyle changes.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The oral version of semaglutide (50 mg daily) achieved nearly the same weight loss as the injectable version.
Most people assume injections are always more effective than pills—this shows a daily pill can match a weekly shot, which could revolutionize accessibility and reduce stigma.
Practical Takeaways
If you’re obese with a comorbidity (like prediabetes or high blood pressure), talk to your doctor about semaglutide as a tool—not a replacement—for lifestyle changes.
Publication
Journal
Pharmaceuticals
Year
2025
Authors
Rui Salvador, Carla Guimarães Moutinho, Carla Sousa, Ana Ferreira Vinha, Márcia Carvalho, Carla Matos
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Claims (3)
Semaglutide helps people who are overweight or obese lose weight by making them feel less hungry and slowing down how fast food leaves their stomach.
People with obesity and another health issue who got a weekly shot of semaglutide plus behavioral therapy lost about 17 kg on average after a year and a half — way more than those who got a placebo.
Taking a weekly shot called semaglutide 2.4 mg helps people who are overweight and have prediabetes lose a lot of weight—about 15 kg in a year—and even after stopping the shot, they still keep off nearly 9 kg. This also helps stop them from developing full-blown diabetes.