Can a vitamin pill help calm puffy, painful eyes in thyroid disease?
Effect of Selenium Supplementation on Mild Graves’ Ophthalmopathy at a Tertiary Hospital – a Six-Month, Open-Labelled, Assessor-Masked, Randomized Controlled Trial
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some people with mild thyroid eye disease have puffy, red, painful eyes. This study gave half the patients a selenium pill every day for six months, while the other half got only eye drops.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 559 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some people with mild thyroid eye disease have puffy, red, painful eyes. This study gave half the patients a selenium pill every day for six months, while the other half got only eye drops.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 559 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Related Content
Claims (5)
People with low selenium levels have more severe eye symptoms from Graves' disease.
Among adult Filipino patients with mild Graves’ ophthalmopathy lasting less than 18 months, taking 200 micrograms of selenium daily for six months along with standard eye care results in 61.9% of eyes reaching a clinical activity score of 0 at six months, compared to 33.3% in those not taking selenium.
In patients with mild Graves’ ophthalmopathy, taking 200 mcg of selenium daily for six months is associated with the absence of eyelid redness in all treated individuals, while 9.52% of untreated individuals experienced eyelid redness.
Among patients with mild Graves’ ophthalmopathy, taking selenium supplements for six months is linked to a lower rate of eye pain compared to those not taking supplements, with 4.76% of supplemented patients reporting pain versus 19.05% of unsupplemented patients.
In patients with mild Graves’ ophthalmopathy, taking 200 mcg of selenium daily for six months is associated with a reduction in swelling of the eye tissues and improved clinical activity scores compared to those not taking selenium.