Can garlic help stop dangerous heart plaque?

Original Title

Aged garlic extract reduces low attenuation plaque in coronary arteries of patients with diabetes: A randomized, double-blind, placebo-controlled study

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Summary

This study tested if a special kind of garlic supplement could stop dangerous fatty buildup in heart arteries of people with diabetes.

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Surprising Findings

Aged garlic extract reduced LAP by 29% while placebo increased it by 57%—a dramatic divergence in just one year.

Most supplements don’t show measurable plaque changes in RCTs, especially not with imaging. This is one of the first to show a targeted, statistically significant effect on a high-risk plaque subtype.

Practical Takeaways

Adults with type 2 diabetes could consider 2,400 mg/day of standardized aged garlic extract (like Kyolic) as a complementary heart-protective strategy.

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68%
Moderate QualityOverall Score

Publication

Journal

Experimental and Therapeutic Medicine

Year

2019

Authors

K. Shaikh, A. Kinninger, Lavanya Cherukuri, D. Birudaraju, R. Nakanishi, S. Almeida, E. Jayawardena, C. Shekar, F. Flores, S. Hamal, M. S. Sheikh, Amit Johanis, Benedict Cu, M. Budoff

Open Access
29 citations
Analysis v1