The Study
Unlocking weight loss potential: Investigating the impact of personalized nutrigenetic-based diet in an Indian population
This study looked at people who chose different diets and saw who lost more weight. But since people picked their own diets, we don’t know if the special diet made the difference—or if those people were just more careful about eating or exercising. It’s like noticing kids who bring lunch from home do better in school—you can’t say lunch caused it, because maybe those kids also study more.
Analysis score
Maximum 58 for a case-control study.
Where the score came from
Scientists gave some obese people diets tailored to their DNA, and others a regular diet, to see who lost more weight and felt better.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 547 / 100
Quality score
Researchers compare people who have a condition (cases) with similar people who do not (controls), looking back in time for differences in exposure. Useful but more prone to bias.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Yes — losing 10% of body weight and lowering blood sugar and uric acid can reduce diabetes and gout risk, which matters for long-term health.
- 2People with DNA-tailored diets lost over 10% of their body weight, dropped body fat, lowered blood sugar, and reduced uric acid — all more than those on regular diets.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
AIMS Molecular Science
Year
2024
Authors
D. Lakshmi, Sati Bhawna, A. Junaid, S. Abinaya, S. Katherine, Lote Ishita, Ahluwalia Geetika, Gosar Hetal, D. Swetha, B. Dhivya, Kocharekar Akshada, Salat Raunaq, R. Aarthi, AR Balamurali, R. Rahul
Related Content
Claims (6)
People who follow an 18-week personalized diet lose more weight and have lower HbA1c levels than those who follow standard dietary advice.
Obese Indian adults who followed a diet tailored to their genes lost more body fat after four months than those who followed a standard diet, even when their total weight did not change differently.
Obese Indian adults who followed a personalized nutrigenetic diet for four months had lower uric acid levels than before starting the diet.
Obese Indian adults who followed a diet tailored to their genetic profile lost more weight and body fat over four months than those who followed a standard diet.
In obese Indian adults, a four-month personalized diet based on genetic information led to lower fasting blood sugar and triglyceride levels than a standard diet.
Obese Indian adults who followed a diet tailored to their genes lost more body weight after four months than those who followed a standard diet.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.