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The Study

The effects of dietary protein intake on appendicular lean mass and muscle function in elderly men: a 10-wk randomized controlled trial.

In simple terms

This study gave two groups of older men different amounts of protein and saw what happened to their muscles. Because they randomly picked who got which diet, we can guess that the protein made the difference—not something else. But we can't be 100% sure because not everyone was blinded.

66%

Analysis score

66/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting0
Methodology60
Publication100
Statistical100
Study type (basis of the score)
Randomized Controlled Trial
Level 1b - Individual RCT
What’s the bottom line?

Older men who ate twice as much protein as the usual recommendation kept more muscle and got stronger legs, while those who ate the usual amount lost muscle—even when both groups ate the same number of calories.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Randomized Trials
Level 1b
66

66 / 100

Quality score

Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.

Can establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Losing 0.64 kg of muscle in 10 weeks can make walking or standing harder for an older person; gaining muscle and power improves daily movement and reduces fall risk.
  2. 2Men eating 1.6 g/kg/day gained 1.49 kg of total muscle and 1.39 kg of trunk muscle, and improved leg power by 26.6 watts.
  3. 3Men eating 0.8 g/kg/day lost 0.64 kg of arm and leg muscle.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

The American journal of clinical nutrition

Year

2017

Authors

C. Mitchell, A. Milan, S. Mitchell, Nina Zeng, F. Ramzan, Pankaja Sharma, S. Knowles, N. Roy, A. Sjödin, K. Wagner, D. Cameron-Smith

Open Access
118 citations
Analysis v5

Related Content

Claims (6)

Assertion

For adults over 65, clinical guidelines state that daily protein intake should be 1.2 to 1.6 grams per kilogram of body weight, spread evenly across meals, with additional focus on consuming protein before sleep.

Descriptive
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Assertion

Among men over 70, consuming 1.6 grams of protein per kilogram of body weight daily for 10 weeks leads to 1.39 kilograms more trunk lean mass gain than consuming 0.8 grams per kilogram daily, even when both groups are in a moderate calorie deficit.

Causal
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Assertion

Elderly men over 70 who consume 0.8 grams of protein per kilogram of body weight daily for 10 weeks lose an average of 0.64 kilograms of muscle in their arms and legs.

Correlational
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Assertion

Among healthy men over 70, eating 1.6 grams of protein per kilogram of body weight daily for 10 weeks increases whole-body lean mass by 1.49 kg, arm and leg lean mass by 0.75 kg, and knee-extension power by 38.3 watts compared to eating 0.8 grams per kilogram per day, regardless of total calorie intake.

Causal
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Assertion

Elderly men over 70 who consume 1.6 grams of protein per kilogram of body weight daily for 10 weeks gain about 26.6 watts of peak power in knee extension, while those consuming 0.8 grams per kilogram per day show no significant change, regardless of total calorie intake.

Causal
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Assertion

In men over 70, consuming 1.6 grams of protein per kilogram of body weight daily leads to greater increases in lean mass and leg power compared to lower intake, even when both groups are in the same state of moderate energy deficit.

Mechanistic
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