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The Study

Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial.

In simple terms

This study is like a carefully run experiment where men were randomly given different protein drinks before bed to see how their muscles used the protein overnight. It shows that 40 grams of protein before sleep helps build more muscle protein while sleeping — it's strong proof for this specific effect.

60%

Analysis score

60/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting0
Methodology80
Publication100
Statistical46
Study type (basis of the score)
Randomized Controlled Trial
Level 1b - Individual RCT
What’s the bottom line?

Older men drank different amounts of protein before sleep, and scientists checked how well their bodies used it overnight to build muscle.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Randomized Trials
Level 1b
60

60 / 100

Quality score

Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.

Can establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes, this means having protein before sleep helps the body repair and build muscle at night.
  2. 2Men who had 40 grams of protein before bed made more muscle protein overnight than those who had less or none.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

The Journal of nutrition

Year

2017

Authors

I. W. Kouw, A. Holwerda, J. Trommelen, I. Kramer, J. Bastiaanse, S. Halson, W. Wodzig, L. Verdijk, L. V. van Loon

Open Access
88 citations
Analysis v5
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.