Can boosting early immune signals stop the body from attacking its own nerves?
The innate immune response affects the development of the autoimmune response in Theiler’s virus- induced demyelinating disease
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave mice a virus that causes nerve damage, then gave some mice a special immune signal (IFN-β) or a fake virus signal (poly(I:C)) right after infection. Other mice got nothing or a blocker for that signal.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 516 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave mice a virus that causes nerve damage, then gave some mice a special immune signal (IFN-β) or a fake virus signal (poly(I:C)) right after infection. Other mice got nothing or a blocker for that signal.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 516 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.