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Assessment of Salivary Interleukin-6 and Cortisol Levels in Patients with Oral Lichen Planus: A Biochemical Correlation with Clinical Severity
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists checked saliva from people with a chronic mouth condition and healthy people to see if two chemicals — one from inflammation and one from stress — were higher in those with worse symptoms.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
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Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists checked saliva from people with a chronic mouth condition and healthy people to see if two chemicals — one from inflammation and one from stress — were higher in those with worse symptoms.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 543 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
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Claims (6)
Prolonged psychological stress increases the severity of autoimmune disease activity by maintaining high levels of stress hormones in the body.
Higher levels of interleukin-6 and cortisol in saliva are consistently linked to more severe cases of oral lichen planus.
People with oral lichen planus have higher levels of interleukin-6 in their saliva than people without the condition, and these higher levels are directly related to how severe their oral tissue damage is.
People with oral lichen planus have higher levels of cortisol in their saliva than people without the condition, and higher cortisol levels are associated with more severe symptoms.
People with oral lichen planus have higher levels of interleukin-6 and cortisol in their saliva than people without the condition, and higher levels of these biomarkers are linked to more severe symptoms.