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The Study

The Effect of Resistance Training Proximity to Failure on Muscular Adaptations and Longitudinal Fatigue in Trained Men

In simple terms

This study is like a fair race between four groups of weightlifters who trained differently—some stopped short of exhaustion, others pushed to the limit. It shows which group got stronger, but it’s not a perfect race because not everyone finished, and the judges couldn’t stay hidden. So we can say one group probably did better, but we can’t be 100% sure it’s because of how hard they trained.

63%

Analysis score

63/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting40
Methodology61
Publication100
Statistical54
Study type (basis of the score)
Randomized Controlled Trial
Level 1b - Individual RCT
What’s the bottom line?

This study tested whether lifting weights until you can't do another rep (to failure) is better than stopping a few reps short — for guys who already train regularly.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Randomized Trials
Level 1b
63

63 / 100

Quality score

Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.

Can establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — you can get just as strong without pushing to failure, and you’re less likely to burn out or get injured by leaving a few reps in the tank.
  2. 2People who stopped 4–6 or 1–3 reps short got about 9–18 kg stronger on bench and squat.
  3. 3Those who trained to failure got much less strong (as little as 0.7 kg) and quit or messed up the workout more often.
  4. 4Muscle size didn't change meaningfully between groups.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

International Journal of Strength and Conditioning

Year

2025

Authors

Zac P Robinson, Christian T. Macarilla, Matthew C. Juber, Rebecca M Cerminaro, Brian Benitez, Joshua C Pelland, Jacob F. Remmert, Thomas A. John, Seth R. Hinson, S. Dinh, Ethan Elkins, Laura C. Canteri, Caitlyn M. Meehan, Erich Helms, Michael C. Zourdos

Open Access
3 citations
Analysis v5

Related Content

Claims (10)

Assertion

Training muscles to the point of failure reduces gains in strength because it increases fatigue without producing significant improvements in nerve signaling or physical force production.

Mechanistic
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Assertion

In trained men, lifting weights with different levels of effort—leaving 1 to 6 reps in reserve or going to failure—does not change levels of fatigue or muscle damage markers over eight weeks.

Descriptive
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Assertion

In trained men, lifting weights until complete muscle fatigue leads to more people quitting and failing to follow the program correctly, resulting in lower long-term adherence and practicality.

Correlational
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Assertion

In trained men, lifting weights close to failure or stopping short of failure results in the same amount of muscle growth, as measured by changes in muscle thickness.

Descriptive
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Assertion

In trained men, lifting weights with some reps left in reserve (4–6 or 1–3 RIR) leads to similar strength gains in bench press and squat as lifting to complete failure (0 RIR) over eight weeks, but lifting to failure may result in slightly smaller gains.

Causal
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Assertion

In trained men, lifting weights with some reps left in reserve (4–6 or 1–3 RIR) leads to similar strength gains in bench press and squat as lifting to complete failure, but lifting to failure is linked to less strength gain and more people quitting the program, suggesting that leaving reps in reserve may be a more sustainable approach.

Causal
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