Why do older people need more Botox?
Relationship Between Muscle Strength Pattern, Facial Wrinkles Classification and Dose of Botulinum Toxin Serotype-A
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Men and women received nearly identical Botox doses—7.4U vs. 7.1U in the corrugator, 4.1U vs. 3.9U in the procerus—despite societal assumptions that women get more treatment.
Most assume cosmetic Botox is gender-skewed, but this study shows dosage is driven by muscle strength and wrinkle depth—not gender.
Practical Takeaways
If you have deep frown lines and strong forehead muscles, expect to need more than the average 7–8 units in the corrugator—don’t be surprised if your provider recommends a higher dose.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Men and women received nearly identical Botox doses—7.4U vs. 7.1U in the corrugator, 4.1U vs. 3.9U in the procerus—despite societal assumptions that women get more treatment.
Most assume cosmetic Botox is gender-skewed, but this study shows dosage is driven by muscle strength and wrinkle depth—not gender.
Practical Takeaways
If you have deep frown lines and strong forehead muscles, expect to need more than the average 7–8 units in the corrugator—don’t be surprised if your provider recommends a higher dose.
Publication
Journal
Modern Research in Plastic and Reconstructive Surgery
Year
2024
Authors
Pithon Napoli Jvm
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Claims (4)
People with stronger forehead muscles and deeper wrinkles between the eyebrows tend to get more Botox injections than those with weaker muscles and lighter wrinkles.
On average, people get about 7 units of Botox between their eyebrows and about 4 units in the forehead line above the nose, and men and women get roughly the same amount.
Older people tend to get more Botox injections than younger people when treating frown lines.
Repeated facial muscle contractions induce dynamic wrinkles that, over time, become fixed static lines due to collagen and elastin degradation; neuromodulators such as botulinum toxin prevent this progression by inhibiting neuromuscular transmission.